Active Trials
Active trials at UCLA Health Alpha Clinic
| Trial Sponsor | Disease Indication | Clinical Trial Name | ClinicalTrials.gov Identifier | IRB # | Phase | STATUS CT.GOV |
|---|---|---|---|---|---|---|
| CIRM | Blood Disorders | Clinical Research Study of Autologous Bone Marrow Transplantation for Sickle Cell Disease (SCD) Using Bone Marrow CD34+ Cells Modified With the Lenti/G-βAS3-FB Lentiviral Vector | NCT02247843 | 13-000288 | Phase 1/2 | Recruiting |
| Merck; CIRM | Cancer | A Phase I Trial of Intratumoral Administration of CCL21-gene Modified Dendritic Cell (DC) Combined With Intravenous Pembrolizumab Foradvanced NSCLC | NCT03546361 | 17-000174 | Phase 1 | Recruiting |
| CIRM; NEI | Vision Loss | Stem Cell-Based Therapy for Limbal Stem Cell Deficiency | NCT03957954 | 19-001056 | Phase 1 | Recruiting |
| Astellas Pharma, Inc. | Vision Loss | A Phase 1b, Multicenter, Dose Escalation, Evaluation of Safety and Tolerability of ASP7317 forGeographic Atrophy Secondary to Age-related Macular Degeneration | NCT03178149 | 17-000835 | Phase 1 | Recruiting |
| CIRM, UCLA | Immune Disease | Efficacy And Safety Of Cryopreserved Autologous Mobilized Peripheral Blood CD34+ Hematopoietic Stem And Progenitor Cells Transduced Ex Vivo With The EFS-ADA Lentiviral Vector In Patients With Severe Combined Immune Deficiency Due To Adenosine Deaminase Deficiency | NCT05432310 | 21-001814 | Phase 1/2 | Recruiting |
| Neurona Therapeutics Inc. | Neurological Disorders | A First-In-Human (FIH) Study of Inhibitory Interneurons (NRTX-1001) in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (MTLE) | NCT05135091 | 21-001132 | Phase 1/2 | Recruiting |
CIRM support
The Alpha Clinics Network funded through CIRM has one unifying goal: to accelerate the development and delivery of stem cell therapies to patients. The UCLA Alpha Clinics Network is able to leverage the strengths of each individual clinic—so that together they form an efficient, scalable and sustainable network that will attract and conduct high-quality clinical trials. The clinics support both CIRM-funded and non CIRM-funded clinical trials by academic or industry sponsors.
Searching trials across UCLA
For information on UCLA clinical trials focused on stem cell research that are active and recruiting, please visit the current clinical trials page. The 'detail' option provides specific information for each trial, including a link to each trial's ClinicalTrials.gov page (via the NCT number). ClinicalTrials.gov is a registry and results database of publicly and privately supported clinical studies of human participants conducted around the world.