Active Trials
Active Trials at UCLA Health Alpha Clinic
| Trial Sponsor | Disease Indication | Clinical Trial Name | ClinicalTrials.gov Identifier | IRB # | Phase | STATUS CT.GOV |
|---|---|---|---|---|---|---|
| CIRM | Blood Disorders | Clinical Research Study of Autologous Bone Marrow Transplantation for Sickle Cell Disease (SCD) Using Bone Marrow CD34+ Cells Modified With the Lenti/G-βAS3-FB Lentiviral Vector | NCT02247843 | 13-000288 | Phase 1/2 | Recruiting |
| Merck; CIRM | Cancer | A Phase I Trial of Intratumoral Administration of CCL21-gene Modified Dendritic Cell (DC) Combined With Intravenous Pembrolizumab For advanced NSCLC | NCT03546361 | 17-000174 | Phase 1 | Recruiting |
| CIRM; NEI | Vision Loss | Stem Cell-Based Therapy for Limbal Stem Cell Deficiency | NCT03957954 | 19-001056 | Phase 1 | Recruiting |
| Astellas Pharma, Inc. | Vision Loss | A Phase 1b, Multicenter, Dose Escalation, Evaluation of Safety and Tolerability of ASP7317 for Geographic Atrophy Secondary to Age-related Macular Degeneration | NCT03178149 | 17-000835 | Phase 1 | Recruiting |
| CIRM, UCLA | Immune Disease | Efficacy And Safety Of Cryopreserved Autologous Mobilized Peripheral Blood CD34+ Hematopoietic Stem And Progenitor Cells Transduced Ex Vivo With The EFS-ADA Lentiviral Vector In Patients With Severe Combined Immune Deficiency Due To Adenosine Deaminase Deficiency | NCT05432310 | 21-001814 | Phase 1/2 | Recruiting |
| Neurona Therapeutics Inc. | Neurological Disorders | A First-In-Human (FIH) Study of Inhibitory Interneurons (NRTX-1001) in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (MTLE) | NCT05135091 | 21-001132 | Phase 1/2 | Recruiting |
| CIRM, NHLBI, UCSF | Blood Disorders | Transplantation of CRISPR-CAS9 Corrected Hematopoietic Stem Cells (CRISPR_SCD001) in Patient with Severe Sickle Cell Disease | NCT04774536 | 21-001649 | Phase 1/2 | Recruiting |
| COH, Metastatic Melanoma Alliance | Cancer | Gene Modified Immune Cells (IL13Ralpha2 CAR T Cells) After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors | NCT04119024 | 19-001145 | Phase 1 | Recruiting |
| CIRM, NHLBI, Children's Hospital Boston | Blood Disorders | A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001) (GRASP) | NCT05353647 | 22-000665 | Phase 1 | Active, not recruiting |
Other Active Clinical Trials at UCLA
To view more active clinical trials at UCLA, please visit our Clinical Trials Opportunities Page. On the page, you can see specific information for each trial, including a link to each trial's ClinicalTrials.gov page (via the NCT number). ClinicalTrials.gov is a registry and results database of publicly and privately supported clinical studies of human participants conducted around the world.